About

At Terremoto, we are creating a seismic shift in the breadth of pursuable targets. Our ultimate goal? To deliver highly targeted, small molecule medicines with optimized clinical profiles and superior therapeutic benefit.

Our Story

Breaking Open the Covalent Drug Universe

The world has witnessed incredible advances in drug development over the last two decades, including new drugs for previously intractable targets. And yet, many patients still face too few treatment options, notably in devastating conditions like cancer.

Enter covalent chemistry.

At Terremoto, we are breaking open the covalent drug universe with the power of lysine-targeted chemistry. In harnessing lysine-based covalency across the disease spectrum, we are focused on developing both best-in-class therapies against known drug targets and first-in-class medicines against the previously undruggable. Our founders helped create this emergent area of science, enabling our team of world-class chemists, biologists and drug developers to pursue a well-defined platform approach and translate treatments to patients as quickly as possible.

We view ourselves as champions for patients. The ultimate driving force behind our work is bringing highly effective medicines to people with devastating diseases as quickly as we possibly can.

The Earth-Shakers

Founded by the Pioneers

With the deep knowledge of our founders, leadership and overall team, we have the ability to translate our ambitious vision into real treatments. Most importantly, our group has set the industry standard for rapidly delivering these medicines to patients – a record we intend to maintain with our platform approach.

Charles Baum, M.D., Ph.D.

Chief Executive Officer

Brian Bestvater

Associate Scientist, Chemistry

Jordan Carelli, Ph.D.

Director, Biology

Jacob Cha, Ph.D.

Director, CMC

Garrett Chado, Ph.D.

Associate Director, Formulation

Regina Choy, Ph.D.

Director, Biology

Chvon Christy

Buyer/Planner, Finance

Hamlet Chu

Senior Director, Business Development

Hang Chu, Ph.D.

Executive Director, Medicinal Chemistry

Bryan Cox, Ph.D.

Senior Director, Computational Chemistry

Brittany Coyne

Senior Associate Scientist, Biology

Janaina Dargell

Associate Director, Human Resources

Subhamoy Das, Ph.D.

Senior Scientist, Biology

Rebecca Freilich, Ph.D.

Senior Scientist 2, Biology

George Gindoyan

Executive Director, Information Technology and Informatics

Caroline Gundel

Research Operations Manager

Timothy Hansen

Associate Scientist

Vivian Ho

Executive Director, Finance and Accounting

Karin Ku

Senior Scientist, Biology

Rusty Lipford, Ph.D.

Chief Scientific Officer

Grace Lu

Chief Business Officer

Charlie Ma, Ph.D.

Senior Director, Structural Biology

Antonett Madriaga

Senior Associate Scientist, Biology

Gigi Moore

Senior Executive Assistant/Office Manager

Deborah Park

Scientist, Biology

Solomon Reisberg, Ph.D.

Executive Director, Head of Research and Portfolio Strategy

James Roquero

Vivarium Research Associate

Andrey Rymar

Senior Associate Scientist, Biology

Sarah Schisla

Senior Research Associate 2

Jacob Schrier, Ph.D.

Senior Scientist 2, Biology

Michael Schulte, Ph.D.

Senior Scientist 2, Biology

Mansoureh Shahryari

Senior Research Associate

Kathleen Shiffer, Ph.D.

Laboratory & Facilities Manager

Wayne Spevak, Ph.D.

Senior Vice President, Chemistry

Nicola Stagg

Executive Director, Head of Toxicology

Jessica Sun, Ph.D.

Executive Director, Head of In Vivo Pharmacology

Saba Tamjidi

Scientist, Biology

Carim van Beek

Associate Director, Drug Substance Manufacturing

Cora Versaggi

Senior Vice President, Human Resources

Melissa Wong

Senior Research Associate 2, Biology

Kin Yang, Ph.D.

Executive Director, Medicinal Chemistry

Adam Zajdlik

Scientist 2, Chemistry

Board of Directors

Charles Baum, M.D., Ph.D.

CEO, Terremoto

Reid Huber, Ph.D.

Partner, Third Rock Ventures

Daniel O’Connell, M.D., Ph.D.

Partner, Novo Holdings Venture Investments

Scott Platshon

Partner, EcoR1 Capital

Peter Thompson, M.D.

Co-founder and Board Chairman, Terremoto
General Partner, OrbiMed

Founders

Matthew Jacobson, Ph.D.

Professor, Dept. of Pharmaceutical Chemistry, UCSF

Jack Taunton, Ph.D.

Professor, Cellular Molecular Pharmacology, UCSF

Peter Thompson, M.D.

Co-founder and Board Chairman, Terremoto
General Partner, OrbiMed Founder

Scientific Advisors

Reid Huber, Ph.D.

Partner, Third Rock Ventures

Kevin Koch, Ph.D.

President, CEO and CFO, Edgewise
Venture Partner, OrbiMed

Jack Taunton, Ph.D.

Professor, Cellular Molecular
Pharmacology, UCSF

Matthew Jacobson, Ph.D.

Professor, Dept. of Pharmaceutical Chemistry, UCSF

John Link, Ph.D.

Former Vice President, Medicinal Chemistry, Gilead Sciences

James Christensen, Ph.D.

Chief Scientific Officer, Mirati

Investors